Future Meetings

ISAN 2024 - Birmingham

University of Birmingham – 25 to 27th July 2024

The local organizing committee of ISAN 2024 are proud to invite those with an interest in autonomic neuroscience, both fundamental and clinical, to this Oxford-Birmingham meeting. While the Oxford meeting has a cardiovascular focus, the Birmingham meeting, hosted in the green heart of our historic campus, with cover the full breadth of autonomic research  – for examples of what will be presented see the accepted symposia below!

Click on the link below for abstract submission and meeting registration.

Accepted Symposia

Bioelectronic Medicine

Chairs: Ellis Meng, University of Southern California and Victor Pikov, Medipace Inc

Stavros Stavrakis, University of Oklahoma – The present and future of vagus nerve stimulation for cardiac arrhythmia

Jeff Ardell, University of California – Axonal modulation therapy for bioelectronic treatment of cardiovascular diseases

Chris Wilson Loma Linda University – Saving premature infants from sudden death using vagus nerve stimulation

Jon Waataja ReShape Lifesciences – Bioelectronics for treating diabetes

Utilising NIH SPARC resources for ANS research

Chairs: Peter Hunter and David Nickerson, Auckland Bioengineering Institute

Jack Cheng & Ariege Bizanti – Spatial mapping of neural data with 3D scaffolds

Nicole Pelot & Joost Wagenaar – Vagus anatomy dashboard

David Paterson (or nominee) University of Oxford – Data visualisation and modelling to support cardiovascular control studies

John Osborn & Maryann Martone – Functional studies of vagal stimulation

Working towards selective vagus nerve stimulation to modulate autonomic function

Chairs: Lindsea Booth, Florey Institute and Alexander Gourine, University College London

Bradford Lowell (or nominee), Harvard Medical School – Highly selective brain-to-gut communication via genetically defined vagus neurons

Nicole Thompson, University College London – Organotopic organization of the porcine mid-cervical vagus nerve

James Fallon, University of Melbourne – Stimulation parameters for directional vagus nerve stimulation

Interrogating the physiology of the human vagus nerve

Chair: Vaughan Macefield Monash University

Nikki Pelot, Duke University – Microscopic anatomy and biophysical properties of the human vagus nerve

Matteo Maria Ottaviani, University of Ancona – Ultrasound-guided microneurography of the human vagus nerve

 David Farmer, Monash University – Single-unit recordings of vagal afferents with cardiac rhythmicity

Mikaela Patros, Monash University – Activation of vagal axons by vagal nerve stimulation

Integrative control

Chairs: Andrew M Allen, University of Melbourne and Julian FR Paton, University of Auckland

Ambre Linossier, Aix-Marseille University – GABAergic neurons of the pre-Bötzinger complex regulate respiratory sinus arrhythmia and blood pressure via the autonomic nervous system.

 Davi  Moraes, University of São Paulo – Medullary parafacial neurons control sympathetic activity and vascular function in physiological and pathophysiological conditions.

 Emma Hart, University of Bristol – New insights into deep stimulation for correcting autonomic imbalance

James P Fisher, University of Auckland – Sympathetic neurocirculatory responses to central chemoreflex activation in human hypertension.

Anatomical, functional, and molecular mapping of autonomic innervation of organs

Chairs: Jack Cheng, University of Central Florida and John Furness, University of Melbourne

Madeleine Di Natale (Australia/USA), Spinal afferent innervation: the stomach-brain atlas

Nick Spencer, Australia – Functional role of spinal afferent endings in the colon using novel wireless optogenetic device

Jerry Yu, USA – Integration of Molecular, Morphological, and Physiological Aspects of Mechanosensors in the Lung

John Tompkins, USA – Morphology, synaptics, and membrane excitability of intracardiac neurons from mice, pigs and humans: targets of clinical neuromodulation for cardiac disease

Hanjun Wang, USA – Cardiac Spinal Afferents: A New Therapeutic Target in Treating Chronic Heart Failure

Neuroimaging of cardiovascular and respiratory control in humans

Chair: Vaughan Macefield, Monash University

Luke Henderson, University of Sydney – Identification of the sympathetic connectome in humans

Rebecca Glarin, University of Melbourne – Ultra-high-field fMRI of human brainstem nuclei involved in the generation of sympathetic outflow

Kevin Shoemaker, University of Western Ontario – The roles of the forebrain in cardiovascular control in exercising humans

Olivia Harrison, University of Otago – Ultra-high-field imaging of networks related to breathing and breathlessness

Neural control and autonomic regulation during exercise: recent innovations

Chair: Satoshi Koba, Tottori University and Marc Kaufman, Penn State College of Medicine

Markus Amann, University of Utah – The exercise pressor reflex: a flow-raising or a pressure-raising mechanism?

Satoshi Koba, Tottori University – Subcortical circuit mechanisms for central command regulation of sympatho-motor coordination

Vaughan Macefield, Monash University – The relative contributions of central command and the metaboreflex to the increases in sympathetic vasoconstrictor drive to contracting muscle

Masaki Mizuno, University of Texas – An integrative approach to better understand the mechanisms of the exercise pressor reflex in health and disease

Bidirectional association between depression and autonomic nervous system alteration: new insights into therapeutic strategies

Chairs: Nicola Montano, University of Milan and Caroline Sévoz-Couche, Sorbonne Université

Julian Koenig, University of Cologne – The impact of SSRI treatment on cortical thickness and autonomic functioning in in adolescents with major depression

Hugo Bottemanne, Sorbonne Université – Evaluation of Ketamine effects on autonomic nervous system in patients with depressive disorders 

Angelica Carandina, University of Milan – The transcutaneous auricular vagus nerve stimulation as a neuromodulatory technique in unipolar and bipolar depression: evidence from DEPONEST study

Andrea Sgoifo, University of Parma – Insights into the autonomic mechanisms of EMDR therapeutical efficacy on depressive symptoms

Central nervous control of blood pressure, brain blood flow, and cognitive health

Chairs: Emma Hart, University of Bristol and Sam Lucas, University of Birmingham

Alex Gourine, University College London – Brain energy metabolism and the regulation of cerebral blood flow

Fiona McBryde, University of Auckland – Defending blood flow to the brain in hypertension, diabetes and ischemic stroke

Emma Hart, University of Bristol – Cerebrovascular variants and the role of the selfish brain in hypertension

Sam Lucas, University of Birmingham – Cerebral blood flow, aging and physiological stress

You’re so vein” – new insights into the function and autonomic regulation of the ‘forgotten’ venous circulation

Chairs: Fiona McBryde and James Fisher, University of Auckland

Tonja Emans, University of Auckland – Sympathetic regulation of the ‘forgotten’ venous circulation – a new therapeutic target for blood pressure control?

Davi Moraes, University of Sao Paulo – Respiratory coupling of mesenteric venous sympathetic nerve activity – the influence of the carotid body

Mickey Fan, University of Auckland – Venous capacity and compliance in hypertensive adults: influence of hypoxia and hyperoxia.

Melanie Dani, Imperial College London – New horizons in the ageing autonomic nervous system: orthostatic hypotension and supine hypertension. 

Breaking news in cardiac autonomic regulation

Chair: Keith Brain, University of Birmingham

Selected submitted abstracts

Recent insights into the role of the vagus nerve in brain-gut communication and therapeutic implications of vagus nerve stimulation in the treatment of gastrointestinal disorders

Chairs: Valentin Pavlov, Feinstein Institutes for Medical Research and Bruno Bonaz, CHU Grenoble

Nicole Pelot, Duke University – Quantified anatomy of human vagus nerves from brainstem to abdomen: defining multi-scale computational models

Sophie Payne, Bionics Institute – Abdominal vagus nerve stimulation as a treatment of IBD: current and new approaches

Qasim Aziz, Queen Mary University of London – Role of the vagus nerve in modulating visceral pain hypersensitivity, intestinal permeability and inflammation in health and GI disease

Bruno Bonaz, CHU Grenoble – Invasive vagus nerve stimulation in Crohn’s disease: A 10-year prospective study follow-up

Targeting GI vasodilatory hormones for the treatment of postprandial syndromes in autonomic disorders

Chairs: Cyndya A. Shibao, Vanderbilt Autonomic Dysfunction Center

Christopher Mathias, Queen Square Institute of Neurology – Postprandial syndromes in autonomic disorders: pathophysiology and treatment

Cyndya A. Shibao, Vanderbilt Autonomic Dysfunction Center – Increased Glucose-dependent insulinotropic polypeptide (GIP) in postprandial syndromes

Simon Veedfald, University of Copenhagen – Neural modulation of entero-pancreatic hormone secretion 

Lærke Smidt, University of Copenhagen – Glucose-dependent insulinotropic polypeptide receptor antagonism in humans

Glucose sensing affecting autonomic activity – A new insight into Neuronal Control of Metabolic Homeostasis

Chairs: Fiona McBryde and Pratik Thakkar, University of Auckland

Stefan Trapp, University College London – Are GLP-1 producing pre-proglucagon neurons of the lower brainstem a useful target for obesity and diabetes treatment?

Silvia V Conde, NOVA Medical School – Carotid body, autonomic function and dysmetabolism: is there something new under the sun?

Pratik Thakkar, University of Auckland – GLP1 receptor agonist ameliorates high blood pressure and high blood sugar in a rat model of “glucotension”

Audrys Pauza, University of Auckland – Glucose sensing by peripheral chemoreceptors: mechanisms and role of incretin hormones